Effect of an Allosteric Modifier of Hemoglobin, RSR-4, on Oxygen Affinity and Oxygen Saturation of Hemoglobin in Rabbits.
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منابع مشابه
Effect of hemodialysis on oxygen-hemoglobin affinity in chronic uremics.
P,,, plasma pH, red cell pH, 2,3-DPG, ATP, lactate, pyruvate, and glycolytic rate were measured before and after hernodialysis in 25 patients on chronic hemodialysis. The prehemodialysis-resting 2,3-DPG level and P,, were elevated in accordance with the degree of anemia. The resting lactate and glycolytic rate were mildly elevated. Plasma and red cell pH increased significantly with dialysis. T...
متن کاملEffects of a synthetic allosteric modifier of hemoglobin oxygen affinity on outcome from global cerebral ischemia in the rat.
BACKGROUND AND PURPOSE Neuronal injury results from an insufficient supply of oxygen to the brain. This experiment examined whether a pharmacologically induced rightward shift of the partial pressure of oxygen at which 50% of hemoglobin is saturated (P50) would improve outcome from either incomplete and/or near-complete forebrain ischemia-induced hypoxia in the rat. METHODS For incomplete isc...
متن کاملSpecific Oxygen Affinity of Hemoglobin in Elasmobranchs
ERS CHARLES P. EMERSON, M.D. , Boston CLEMENT A. FINCH, M.D., Boston ROBERT S. EVANS, M.D. , San Francisco LAWRENCE E. YOUNG, M.D. , Rochester, N. Y. OLIVER P. JoNas, Pn.D. , Buffalo JEAN P. SOULIER, M.D. , ParIs SOLOMON ESTREN, M.D., New York JAN WALDENSTROM. , M.D. , Upsala, Sweden RAMON M. SUAREZ, San Juan, Puerto Rico HEMOGLOBIN, METHEMOGLOBIN AND BILIRUBIN METABOLISM SPECIFIC OXYGEN AFFINI...
متن کاملSpecific Oxygen Affinity of Hemoglobin in Elasmobranchs
ERS CHARLES P. EMERSON, M.D. , Boston CLEMENT A. FINCH, M.D., Boston ROBERT S. EVANS, M.D. , San Francisco LAWRENCE E. YOUNG, M.D. , Rochester, N. Y. OLIVER P. JoNas, Pn.D. , Buffalo JEAN P. SOULIER, M.D. , ParIs SOLOMON ESTREN, M.D., New York JAN WALDENSTROM. , M.D. , Upsala, Sweden RAMON M. SUAREZ, San Juan, Puerto Rico HEMOGLOBIN, METHEMOGLOBIN AND BILIRUBIN METABOLISM SPECIFIC OXYGEN AFFINI...
متن کاملOxygen Affinity of Hemoglobin in Persons
THE OXYGEN affinity of hemoglobin (Bohr effect)1 may vary in different subjects. Under conditions of organ ischemia, these variations may be of significance. A study was undertaken to assess the affinity of hemoglobin for oxygen among patients in various states. Included in the study were patients with typical acute myocardial infarction, subjects with clinical and electrocardiographic signs of...
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ژورنال
عنوان ژورنال: The Japanese Journal of Physiology
سال: 1998
ISSN: 0021-521X
DOI: 10.2170/jjphysiol.48.439